Response of the magnocellular system in rats to hypovolemia and cholecystokinin during pregnancy and lactation

To define changes in the magnocellular neuroendocrine system during lactation and pregnancy, plasma levels of oxytocin (OT) and vasopressin (VP) were compared after polyethylene glycol (PEG)-induced hypovolemia and cholecystokinin stimulation. The threshold for Vp release was always lower than that...

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Veröffentlicht in:	American journal of physiology. Regulatory, integrative and comparative physiology integrative and comparative physiology, 1994-04, Vol.35 (4), p.R1327-R1337
Hauptverfasser:	KOEHLER, E. M, MCLEMORE, G. L, MARTEL, J. K, SUMMY-LONG, J. Y
Format:	Artikel
Sprache:	eng
Schlagworte:	Anatomy & physiology Animal reproduction Biological and medical sciences Breastfeeding & lactation Fundamental and applied biological sciences. Psychology Mother. Fetoplacental unit. Mammary gland. Milk Pregnancy. Parturition. Lactation Rodents Vertebrates: reproduction
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Beschreibung
Zusammenfassung:	To define changes in the magnocellular neuroendocrine system during lactation and pregnancy, plasma levels of oxytocin (OT) and vasopressin (VP) were compared after polyethylene glycol (PEG)-induced hypovolemia and cholecystokinin stimulation. The threshold for Vp release was always lower than that for OT, indicative of preferential release of VP with less than 5% or a 20% loss in blood volume.
ISSN:	0363-6119 1522-1490