Endothelial NO and prostanoid involvement in newborn and juvenile pig pial arteriolar vasomotor responses

Specific cerebrovascular dilatory responses in newborn piglets are entirely prostanoid dependent, but require both nitric oxide (NO) and prostanoids in juveniles. We examined endothelial dependency and mechanisms of NO- and prostanoid-mediated cerebrovascular responses in anethetized newborn and nuv...

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Veröffentlicht in:American journal of physiology. Heart and circulatory physiology 2001-12, Vol.50 (6), p.H2366-H2377
Hauptverfasser: WILLIS, Adam P, LEFFLER, Charles W
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Sprache:eng
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Zusammenfassung:Specific cerebrovascular dilatory responses in newborn piglets are entirely prostanoid dependent, but require both nitric oxide (NO) and prostanoids in juveniles. We examined endothelial dependency and mechanisms of NO- and prostanoid-mediated cerebrovascular responses in anethetized newborn and nuvenile pigs implanted with close cranial windows.
ISSN:0363-6135
1522-1539