Chronic metabolic sequelae of traumatic brain injury : Prolonged suppression of somatosensory activation

Injuries to the brain acutely disrupt normal metabolic function and may deactivate functional circuits. It is unknown whether these metabolic abnormalities improve over time. We used 2-deoxyglucose (2-DG) autoradiographic image-averaging to assess local cerebral glucose utilization (lCMRGlc) of the...

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Veröffentlicht in:	American journal of physiology. Heart and circulatory physiology 2000-09, Vol.48 (3), p.H924-H931
Hauptverfasser:	PASSINEAU, M. J, ZHAO, W, BUSTO, R, DIETRICH, W. D, ALONSO, O, LOOR, J. Y, BRAMLETT, H. M, GINSBERG, M. D
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry Biological and medical sciences Brain Circulatory system Injuries Injuries of the nervous system and the skull. Diseases due to physical agents Medical sciences Neurology Traumas. Diseases due to physical agents
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Zusammenfassung:	Injuries to the brain acutely disrupt normal metabolic function and may deactivate functional circuits. It is unknown whether these metabolic abnormalities improve over time. We used 2-deoxyglucose (2-DG) autoradiographic image-averaging to assess local cerebral glucose utilization (lCMRGlc) of the rat brain 2 mo after moderate (1.7-2.1 atm) fluid-percussion traumatic brain injury (FPI).
ISSN:	0363-6135 1522-1539