Increased medial smooth muscle cell length is responsible for vascular hypertrophy in young hypertensive rats
Large mesenteric arteries from 3- to 4-wk-old spontaneously hypertensive rats (SHR) showed medial hypertrophy and an increased contractile response to various agonists before significant blood pressure increase. Here we determined the cellular nature of this vascular hypertrophy.
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| Veröffentlicht in: | American journal of physiology. Heart and circulatory physiology 2000-11, Vol.48 (5), p.H2085-H2094 |
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| container_end_page | H2094 |
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| container_issue | 5 |
| container_start_page | H2085 |
| container_title | American journal of physiology. Heart and circulatory physiology |
| container_volume | 48 |
| creator | DICKHOUT, J. G LEE, R. M. K. W |
| description | Large mesenteric arteries from 3- to 4-wk-old spontaneously hypertensive rats (SHR) showed medial hypertrophy and an increased contractile response to various agonists before significant blood pressure increase. Here we determined the cellular nature of this vascular hypertrophy. |
| format | Article |
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G ; LEE, R. M. K. W</creator><creatorcontrib>DICKHOUT, J. G ; LEE, R. M. K. W</creatorcontrib><description>Large mesenteric arteries from 3- to 4-wk-old spontaneously hypertensive rats (SHR) showed medial hypertrophy and an increased contractile response to various agonists before significant blood pressure increase. Here we determined the cellular nature of this vascular hypertrophy.</description><identifier>ISSN: 0363-6135</identifier><identifier>EISSN: 1522-1539</identifier><identifier>CODEN: AJPPDI</identifier><language>eng</language><publisher>Bethesda, MD: American Physiological Society</publisher><subject>Arterial hypertension. Arterial hypotension ; Biological and medical sciences ; Blood and lymphatic vessels ; Cardiology. Vascular system ; Cells ; Clinical manifestations. Epidemiology. Investigative techniques. Etiology ; Heart ; Hypertension ; Medical sciences ; Muscular system ; Rodents</subject><ispartof>American journal of physiology. 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Heart and circulatory physiology</title><description>Large mesenteric arteries from 3- to 4-wk-old spontaneously hypertensive rats (SHR) showed medial hypertrophy and an increased contractile response to various agonists before significant blood pressure increase. Here we determined the cellular nature of this vascular hypertrophy.</description><subject>Arterial hypertension. Arterial hypotension</subject><subject>Biological and medical sciences</subject><subject>Blood and lymphatic vessels</subject><subject>Cardiology. Vascular system</subject><subject>Cells</subject><subject>Clinical manifestations. Epidemiology. Investigative techniques. 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Etiology</topic><topic>Heart</topic><topic>Hypertension</topic><topic>Medical sciences</topic><topic>Muscular system</topic><topic>Rodents</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>DICKHOUT, J. G</creatorcontrib><creatorcontrib>LEE, R. M. K. W</creatorcontrib><collection>Pascal-Francis</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>Physical Education Index</collection><collection>Toxicology Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><jtitle>American journal of physiology. Heart and circulatory physiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>DICKHOUT, J. G</au><au>LEE, R. M. K. W</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Increased medial smooth muscle cell length is responsible for vascular hypertrophy in young hypertensive rats</atitle><jtitle>American journal of physiology. Heart and circulatory physiology</jtitle><date>2000-11-01</date><risdate>2000</risdate><volume>48</volume><issue>5</issue><spage>H2085</spage><epage>H2094</epage><pages>H2085-H2094</pages><issn>0363-6135</issn><eissn>1522-1539</eissn><coden>AJPPDI</coden><abstract>Large mesenteric arteries from 3- to 4-wk-old spontaneously hypertensive rats (SHR) showed medial hypertrophy and an increased contractile response to various agonists before significant blood pressure increase. Here we determined the cellular nature of this vascular hypertrophy.</abstract><cop>Bethesda, MD</cop><pub>American Physiological Society</pub></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0363-6135 |
| ispartof | American journal of physiology. Heart and circulatory physiology, 2000-11, Vol.48 (5), p.H2085-H2094 |
| issn | 0363-6135 1522-1539 |
| language | eng |
| recordid | cdi_proquest_journals_229689664 |
| source | American Physiological Society; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Arterial hypertension. Arterial hypotension Biological and medical sciences Blood and lymphatic vessels Cardiology. Vascular system Cells Clinical manifestations. Epidemiology. Investigative techniques. Etiology Heart Hypertension Medical sciences Muscular system Rodents |
| title | Increased medial smooth muscle cell length is responsible for vascular hypertrophy in young hypertensive rats |
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