Increased medial smooth muscle cell length is responsible for vascular hypertrophy in young hypertensive rats

Large mesenteric arteries from 3- to 4-wk-old spontaneously hypertensive rats (SHR) showed medial hypertrophy and an increased contractile response to various agonists before significant blood pressure increase. Here we determined the cellular nature of this vascular hypertrophy.

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	American journal of physiology. Heart and circulatory physiology 2000-11, Vol.48 (5), p.H2085-H2094
Hauptverfasser:	DICKHOUT, J. G, LEE, R. M. K. W
Format:	Artikel
Sprache:	eng
Schlagworte:	Arterial hypertension. Arterial hypotension Biological and medical sciences Blood and lymphatic vessels Cardiology. Vascular system Cells Clinical manifestations. Epidemiology. Investigative techniques. Etiology Heart Hypertension Medical sciences Muscular system Rodents
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Large mesenteric arteries from 3- to 4-wk-old spontaneously hypertensive rats (SHR) showed medial hypertrophy and an increased contractile response to various agonists before significant blood pressure increase. Here we determined the cellular nature of this vascular hypertrophy.
ISSN:	0363-6135 1522-1539