Cardiac endothelial transport and metabolism of adenosine and inosine

The influence of transmembrane flux limitations on cellular metabolism of purine nucleosides was assessed in whole organ studies. Transcapillary transport of the purine nucleosides adenosine (Ado) and inosine (Ino) via paracellular diffusion through interendothelial clefts in parallel with carrier-m...

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Veröffentlicht in:	American journal of physiology. Heart and circulatory physiology 1999-09, Vol.46 (3), p.H1241-H1251
Hauptverfasser:	SCHWARTZ, L. M, BUKOWSKI, T. R, REVKIN, J. H, BASSINGTHWAIGHTE, J. B
Format:	Artikel
Sprache:	eng
Schlagworte:	Anatomy & physiology Biochemistry Biological and medical sciences Cardiology Cells Fundamental and applied biological sciences. Psychology Heart Metabolism Vertebrates: cardiovascular system
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Beschreibung
Zusammenfassung:	The influence of transmembrane flux limitations on cellular metabolism of purine nucleosides was assessed in whole organ studies. Transcapillary transport of the purine nucleosides adenosine (Ado) and inosine (Ino) via paracellular diffusion through interendothelial clefts in parallel with carrier-mediated transendothelial fluxes was studied in isolated, Krebs-Henseleit-perfused rabbit and guinea pig hearts.
ISSN:	0363-6135 1522-1539