Transient blood-brain barrier passage of polar compounds at low pH

The brain uptake index of polar C-labeled test compounds with molecular weights of 79-70,000 is examined using the single-pass carotid injection technique in pentobarbital-anesthetized rats.

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Veröffentlicht in:American journal of physiology. Heart and circulatory physiology 1994-12, Vol.36 (6), p.H2229-H2236
Hauptverfasser: OLDENDORF, W. H, STOLLER, B. E, TISHLER, T. A, WILLIAMS, J. L, OLDENDORF, S. Z
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container_issue 6
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container_title American journal of physiology. Heart and circulatory physiology
container_volume 36
creator OLDENDORF, W. H
STOLLER, B. E
TISHLER, T. A
WILLIAMS, J. L
OLDENDORF, S. Z
description The brain uptake index of polar C-labeled test compounds with molecular weights of 79-70,000 is examined using the single-pass carotid injection technique in pentobarbital-anesthetized rats.
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ispartof American journal of physiology. Heart and circulatory physiology, 1994-12, Vol.36 (6), p.H2229-H2236
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subjects Biological and medical sciences
Blood vessels
Brain
Cerebral circulation. Blood-brain barrier. Choroid plexus. Cerebrospinal fluid. Circumventricular organ. Meninges
Circulatory system
Fundamental and applied biological sciences. Psychology
Rodents
Vertebrates: nervous system and sense organs
title Transient blood-brain barrier passage of polar compounds at low pH
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