Transient blood-brain barrier passage of polar compounds at low pH
The brain uptake index of polar C-labeled test compounds with molecular weights of 79-70,000 is examined using the single-pass carotid injection technique in pentobarbital-anesthetized rats.
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Veröffentlicht in: | American journal of physiology. Heart and circulatory physiology 1994-12, Vol.36 (6), p.H2229-H2236 |
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container_issue | 6 |
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container_title | American journal of physiology. Heart and circulatory physiology |
container_volume | 36 |
creator | OLDENDORF, W. H STOLLER, B. E TISHLER, T. A WILLIAMS, J. L OLDENDORF, S. Z |
description | The brain uptake index of polar C-labeled test compounds with molecular weights of 79-70,000 is examined using the single-pass carotid injection technique in pentobarbital-anesthetized rats. |
format | Article |
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identifier | ISSN: 0363-6135 |
ispartof | American journal of physiology. Heart and circulatory physiology, 1994-12, Vol.36 (6), p.H2229-H2236 |
issn | 0363-6135 1522-1539 |
language | eng |
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subjects | Biological and medical sciences Blood vessels Brain Cerebral circulation. Blood-brain barrier. Choroid plexus. Cerebrospinal fluid. Circumventricular organ. Meninges Circulatory system Fundamental and applied biological sciences. Psychology Rodents Vertebrates: nervous system and sense organs |
title | Transient blood-brain barrier passage of polar compounds at low pH |
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