Transient blood-brain barrier passage of polar compounds at low pH

The brain uptake index of polar C-labeled test compounds with molecular weights of 79-70,000 is examined using the single-pass carotid injection technique in pentobarbital-anesthetized rats.

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Bibliographische Detailangaben
Veröffentlicht in:	American journal of physiology. Heart and circulatory physiology 1994-12, Vol.36 (6), p.H2229-H2236
Hauptverfasser:	OLDENDORF, W. H, STOLLER, B. E, TISHLER, T. A, WILLIAMS, J. L, OLDENDORF, S. Z
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Blood vessels Brain Cerebral circulation. Blood-brain barrier. Choroid plexus. Cerebrospinal fluid. Circumventricular organ. Meninges Circulatory system Fundamental and applied biological sciences. Psychology Rodents Vertebrates: nervous system and sense organs
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Beschreibung
Zusammenfassung:	The brain uptake index of polar C-labeled test compounds with molecular weights of 79-70,000 is examined using the single-pass carotid injection technique in pentobarbital-anesthetized rats.
ISSN:	0363-6135 1522-1539