Blockade of endothelium-dependent responses in conscious rats by cyclosporin A : effect of L-arginine

Blockade of endothelium-dependent responses in conscious rats by cyclosporin A : effect of L-arginine

The effect of the major immunosuppressive drug, cyclosporin A (CyA), on endothelial function was examined in rats. Data suggest that, in early stages of CyA toxicity, the predominant functional alteration occurs at the endothelial level.

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Veröffentlicht in:American journal of physiology. Heart and circulatory physiology 1993-03, Vol.33 (3), p.H708-H714
Hauptverfasser: GALLEGO, M. J, LOPEZ FARRE, A, RIESCO, A, MONTON, M, GRANDES, S. M, BARAT, A, HERNANDO, L, CASADO, S, CARAMELO, C. A
Format: Artikel
Sprache:eng
Schlagworte:
Biological and medical sciences
Cellular biology
Drugs
Immunomodulators
Medical sciences
Pharmacology. Drug treatments
Rodents
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Zusammenfassung:The effect of the major immunosuppressive drug, cyclosporin A (CyA), on endothelial function was examined in rats. Data suggest that, in early stages of CyA toxicity, the predominant functional alteration occurs at the endothelial level.
ISSN:0363-6135
1522-1539