Expression of human smooth muscle calponin in transgenic mice revealed with a bacterial artificial chromosome

Defining regulatory elements governing cell-restricted gene expression can be difficult because cis-elements may reside tens of kilobases away from start site(s) of transcription. Miano et al report on the use of a bacterial artificial chromosome (BAC) to begin understanding the in vivo regulation o...

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Veröffentlicht in:American journal of physiology. Heart and circulatory physiology 2002-05, Vol.51 (5), p.H1793-H1803
Hauptverfasser: MIANO, Joseph M, KITCHEN, Chad M, JIYUAN CHEN, MALTBY, Kathleen M, KELLY, Louise A, WEILER, Hartmut, KRAHE, Ralf, ASHWORTH, Linda K, GARCIA, Emilio
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Sprache:eng
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Zusammenfassung:Defining regulatory elements governing cell-restricted gene expression can be difficult because cis-elements may reside tens of kilobases away from start site(s) of transcription. Miano et al report on the use of a bacterial artificial chromosome (BAC) to begin understanding the in vivo regulation of smooth muscle calponin (SM-Calp).
ISSN:0363-6135
1522-1539