Expression of human smooth muscle calponin in transgenic mice revealed with a bacterial artificial chromosome
Defining regulatory elements governing cell-restricted gene expression can be difficult because cis-elements may reside tens of kilobases away from start site(s) of transcription. Miano et al report on the use of a bacterial artificial chromosome (BAC) to begin understanding the in vivo regulation o...
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Veröffentlicht in: | American journal of physiology. Heart and circulatory physiology 2002-05, Vol.51 (5), p.H1793-H1803 |
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Sprache: | eng |
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Zusammenfassung: | Defining regulatory elements governing cell-restricted gene expression can be difficult because cis-elements may reside tens of kilobases away from start site(s) of transcription. Miano et al report on the use of a bacterial artificial chromosome (BAC) to begin understanding the in vivo regulation of smooth muscle calponin (SM-Calp). |
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ISSN: | 0363-6135 1522-1539 |