Role of erythrocyte in regulating local O2 delivery mediated by hemoglobin oxygenation

The release of ATP from red blood cells (RBC) in response to low O2 levels is linked to ATP production and the oxygenation state of hemoglobin. Because O2 is unloaded from the RBC, the concentration of deoxygenated hemoglobin increases, displacing phosphofructokinase from the cytoplasmic domain of b...

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Veröffentlicht in:American journal of physiology. Heart and circulatory physiology 2001-06, Vol.49 (6), p.H2833-H2839
Hauptverfasser: JAGGER, Justin E, BATEMAN, Ryon M, ELLSWORTH, Mary L, ELLIS, Chris G
Format: Artikel
Sprache:eng
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Zusammenfassung:The release of ATP from red blood cells (RBC) in response to low O2 levels is linked to ATP production and the oxygenation state of hemoglobin. Because O2 is unloaded from the RBC, the concentration of deoxygenated hemoglobin increases, displacing phosphofructokinase from the cytoplasmic domain of band 3.
ISSN:0363-6135
1522-1539