Neuronal NOS-dependent dilation to flow in coronary arteries of male eNOS-KO mice

Neuronal NOS-dependent dilation to flow in coronary arteries of male eNOS-KO mice

Flow-induced dilation was examined in siolated coronary arteries of endothelial nitric oxide (NO) synthase knockout mice (eNOS-KO) and wild-type (WT) mice. The basal tone of arteries (percentage of passive diameter) was significantly greater in eNOS-KO than in WT mice; their flow-induced dilations,...

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Veröffentlicht in:American journal of physiology. Heart and circulatory physiology 2002-02, Vol.51 (2), p.H429-H436
Hauptverfasser: AN HUANG, DONG SUN, SHESELY, Edward G, LEVEE, Ellen M, KOLLER, Akos, KALEY, Gabor
Format: Artikel
Sprache:eng
Schlagworte:
Biological and medical sciences
Coronary vessels
Free radicals
Fundamental and applied biological sciences. Psychology
Heart
Rodents
Vertebrates: cardiovascular system
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Zusammenfassung:Flow-induced dilation was examined in siolated coronary arteries of endothelial nitric oxide (NO) synthase knockout mice (eNOS-KO) and wild-type (WT) mice. The basal tone of arteries (percentage of passive diameter) was significantly greater in eNOS-KO than in WT mice; their flow-induced dilations, however, were similar.
ISSN:0363-6135
1522-1539