ATP-mediated release of arachidonic acid metabolites from venular endothelium causes arteriolar dilation

This study was designed to test the hypothesis that venular administration of ATP resulted in endothelium-dependent dilation of adjacent arterioles through a mechanism involving cyclooxygenase products. Forty-three male golden hamsters were anesthetized with pentobarbital sodium (60 mg/kg ip), and t...

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Veröffentlicht in:	American journal of physiology. Heart and circulatory physiology 2001-06, Vol.49 (6), p.H2616-H2622
Hauptverfasser:	HAMMER, Leah W, LIGON, Alison L, HESTER, Robert L
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Blood vessels Blood vessels and receptors Cells Fundamental and applied biological sciences. Psychology Metabolism Rodents Vertebrates: cardiovascular system
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Beschreibung
Zusammenfassung:	This study was designed to test the hypothesis that venular administration of ATP resulted in endothelium-dependent dilation of adjacent arterioles through a mechanism involving cyclooxygenase products. Forty-three male golden hamsters were anesthetized with pentobarbital sodium (60 mg/kg ip), and the cremaster muscle was prepared for in vivo microscopy.
ISSN:	0363-6135 1522-1539