AE anion exchangers in atrial tumor cells

Intracellular pH homeostasis and intracellular Cl- concentration in cardiac myocytes are regulated by anion exchange mechanisms. In physiological extracellular Cl- concentrations, Cl-/HCO- exchange promotes intracellular acidification and Cl- loading sensitive to inhibition by stilbene disulfonates.

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Veröffentlicht in:American journal of physiology. Heart and circulatory physiology 2001-03, Vol.49 (3), p.H937-H945
Hauptverfasser: PAPAGEORGIOU, Panos, SHMUKLER, Boris E, STUART-TILLEY, Alan K, LIANWEI JIANG, ALPER, Seth L
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Sprache:eng
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Zusammenfassung:Intracellular pH homeostasis and intracellular Cl- concentration in cardiac myocytes are regulated by anion exchange mechanisms. In physiological extracellular Cl- concentrations, Cl-/HCO- exchange promotes intracellular acidification and Cl- loading sensitive to inhibition by stilbene disulfonates.
ISSN:0363-6135
1522-1539