Gender and transcriptional regulation of NO synthase and ET-1 in porcine aortic endothelial cells

Wang et al use aortic endothelial cells from pigs to determine whether normal fluctuations in sex steroid hormones alter gene transcription for endothelial nitric oxide synthase (NOS) and preproendothelin-1 (prepro-ET-1). Some of the results suggest that expression of endothelial NOS and prepro-ET-1...

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Veröffentlicht in:American journal of physiology. Heart and circulatory physiology 1997-10, Vol.42 (4), p.H1962-H1967
Hauptverfasser: WANG, X, BARBER, D. A, LEWIS, D. A, MCGREGOR, C. G. A, SIECK, G. C, FITZPATRICK, L. A, MILLER, V. M
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Sprache:eng
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Zusammenfassung:Wang et al use aortic endothelial cells from pigs to determine whether normal fluctuations in sex steroid hormones alter gene transcription for endothelial nitric oxide synthase (NOS) and preproendothelin-1 (prepro-ET-1). Some of the results suggest that expression of endothelial NOS and prepro-ET-1 may be regulated at transcriptional level by ovarian hormones.
ISSN:0363-6135
1522-1539