Matrix metalloproteinase expression and activity in isolated myocytes after neurohormonal stimulation

Changes in myocardial matrix metalloproteinase (MMP) activity and expression have been associated with left ventricular (LV) remodeling. A recent study demonstrated that LV myocytes synthesize and release MMPs, which suggests that LV myocytes may participate in myocardial remodeling.

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Bibliographische Detailangaben
Veröffentlicht in:	American journal of physiology. Heart and circulatory physiology 2001-08, Vol.50 (2), p.H543-H551
Hauptverfasser:	COKER, Mytsi L, JOLLY, Jennifer R, JOFFS, Cassandra, ETOH, Takuma, HOLDER, Jennifer R, BOND, Brian R, SPINALE, Francis G
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cardiovascular disease Enzymes Fundamental and applied biological sciences. Psychology Heart Hormones Proteins Vertebrates: cardiovascular system
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Beschreibung
Zusammenfassung:	Changes in myocardial matrix metalloproteinase (MMP) activity and expression have been associated with left ventricular (LV) remodeling. A recent study demonstrated that LV myocytes synthesize and release MMPs, which suggests that LV myocytes may participate in myocardial remodeling.
ISSN:	0363-6135 1522-1539