A new integrative method to quantify total Ca2+ handling and futile Ca2+ cycling in failing hearts

Ca2+ handling in excitation-contraction coupling requires considerable O2 consumption (VO2) in cardiac contraction. We have developed an integrative method to quantify total Ca2+ handling in normal hearts.

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Bibliographische Detailangaben
Veröffentlicht in:	American journal of physiology. Heart and circulatory physiology 1998-12, Vol.44 (6), p.H2325-H2333
Hauptverfasser:	SHIMIZU, J, ARAKI, J, SUGA, H, MIZUNO, J, LEE, S, SYUU, Y, HOSOGI, S, MOHRI, S, MIKANE, T, TAKAKI, M, TAYLOR, T. W
Format:	Artikel
Sprache:	eng
Schlagworte:	Anatomy & physiology Biological and medical sciences Calcium Fundamental and applied biological sciences. Psychology Heart Heart failure Ions Vertebrates: cardiovascular system
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	Ca2+ handling in excitation-contraction coupling requires considerable O2 consumption (VO2) in cardiac contraction. We have developed an integrative method to quantify total Ca2+ handling in normal hearts.
ISSN:	0363-6135 1522-1539