Ischemia-induced phosphorylation and translocation of stress protein alphaB-crystallin to Z lines of myocardium

It is becoming clear that stress proteins play a role in various aspects of postischemic myocardial recovery and that the cytoskeleton of cardiac myocytes is an important determinant for cellular survival during ischemia and energy depletion. In the present study, we addressed the question of whether the cytoskeleton-binding stress protein alphaB-crystallin may be involved in early cellular responses of rat and porcine myocardium to ischemia.