Inhibitory effects of cocaine on Ca(2plus) transients and contraction in single cardiomyocytes

A study of the inhibitory effects of cocaine on calcium ion transients and contraction in single cardiomyocytes in rats suggests that sarcolemmal ion channels are the primary site that, in cardiac muscle, mediate the negative inotropic effects and the suppression of calcium ion transients by cocaine...

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Veröffentlicht in:American journal of physiology. Heart and circulatory physiology 1994-02, Vol.35 (2), p.H555
Hauptverfasser: Renard, Dominique C, Delaville, Fernando J, Thomas, Andrew P
Format: Artikel
Sprache:eng
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Zusammenfassung:A study of the inhibitory effects of cocaine on calcium ion transients and contraction in single cardiomyocytes in rats suggests that sarcolemmal ion channels are the primary site that, in cardiac muscle, mediate the negative inotropic effects and the suppression of calcium ion transients by cocaine.
ISSN:0363-6135
1522-1539