Catalyst-enabled Site-selectivity in the Iridium-catalyzed C–H Borylation of Arenes

The direct and selective replacement of C–H bonds in aromatic compounds with C–B bonds represents an ideal approach to arylboron compounds. Despite the tremendous advances during the past fifteen years, controlling the site-selectivity has remained a central challenge in this field. This Highlight Review summarizes the recent progress on the site-selective C–H borylation of arenes with a particular focus on the factors guiding the site-selectivity, especially catalyst-controlled site-selectivity.