Microbiome yarns: The Global Phenotype‐Genotype Survey

[...]to return to the issue of economic and legal aspects of microbiota sharing, we all know by now that a number of clinical conditions caused either by pathogenic microbes or an unhealthy microbial flora, or to use the current technical term dysbiosis , have been successfully treated by transplant...

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Veröffentlicht in:Microbial Biotechnology 2019-01, Vol.12 (1), p.11-24
Hauptverfasser: Timmis, Kenneth, Jebok, Franziska, Rohde, Manfred, Molinari, Gabriella
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Sprache:eng
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Zusammenfassung:[...]to return to the issue of economic and legal aspects of microbiota sharing, we all know by now that a number of clinical conditions caused either by pathogenic microbes or an unhealthy microbial flora, or to use the current technical term dysbiosis , have been successfully treated by transplants of ‘healthy’ or ‘normal’ microbial communities obtained from donors. [...]as you will recall, to obtain some answers to these and other burning questions, the most ambitious microbiome survey to date, the Global Phenotype‐Genotype Survey, was carried out by an international research group assembled by a global consortium of health agencies, in order to confirm existing correlations of influences of microbiota on phenotypes, and to discover new ones. According to Professor Tim Kennis of the Queenton Institute of Advanced Studies, since the diversity of human genomes, and their phenotypic consequences – that is, the physiological differences between us – influence the composition of the resident microbiomes, and since the resident microbiomes superimpose their own physiological modifications, there has been and still is co‐evolution of the two partners of the biome. [...]camel antibodies that specifically bind to ligands/antigens present on the surface of selected gut microbes essential for restoring normality in a dysbiosis situation are displayed on the surface of Synkey.
ISSN:1751-7915
1751-7915
DOI:10.1111/1751-7915.13341