Lithium–Bromide Exchange versus Nucleophilic Addition of Schiff's Base: Unprecedented Tandem Cyclisation Pathways

Invited for the cover of this issue is the group of Philip C. Andrews and Victoria L. Blair at Monash University, Melbourne. The image depicts the La Trobe reading room in Melbourne's State Library as a way of illustrating the manuscript′s discussion of textbook techniques. Read the full text of the article at 10.1002/chem.201902140. “Lithium–halogen exchange reactions remain one of the most fundamental synthetic transformation strategies. Our study, of this text‐book methodology, has revealed competitive addition pathways exist when applied to aromatic Schiff's bases, resulting in the unexpected formation of a range of privileged N‐heterocycles.” Read more about the story behind the cover in the Cover Profile and about the research itself on page 11876 ff. (DOI: 10.1002/chem.201902140).