Demographic and Therapeutic Determinants of Pain Reactivity in Very Low Birth Weight Neonates at 32 Weeks' Postconceptional Age

Demographic and Therapeutic Determinants of Pain Reactivity in Very Low Birth Weight Neonates at 32 Weeks' Postconceptional Age

Management of pain in very low birth weight infants is limited by a lack of empiric knowledge about the multiple determinants of biobehavioral reactivity in infants receiving neonatal intensive care. To examine relationship of early neonatal factors and previous medication exposure to subsequent bio...

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Veröffentlicht in:Pediatrics (Evanston) 2001-01, Vol.107 (1), p.105-112
Hauptverfasser: Grunau, Ruth Eckstein, Oberlander, Tim F, Whitfield, Michael F, Fitzgerald, Colleen, Lee, Shoo K
Format: Artikel
Sprache:eng
Schlagworte:
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Babies
Biological and medical sciences
Birth weight
Blood Specimen Collection - adverse effects
Cohort Studies
Dexamethasone - administration & dosage
Electrocardiography
Emergency and intensive care: neonates and children. Prematurity. Sudden death
Facial Expression
Female
Fentanyl - administration & dosage
Heart Rate
Humans
Indomethacin - administration & dosage
Infant
Infant, Newborn
Infant, Very Low Birth Weight
Infants (Premature)
Intensive care medicine
Male
Medical sciences
Monitoring, Physiologic
Morphine - administration & dosage
Narcotics
Pain
Pain - drug therapy
Pain - etiology
Pain - physiopathology
Pain in children
Pain management
Pain Measurement
Pain Threshold
Pancuronium - administration & dosage
Pediatric pain
Pediatrics
Physiological aspects
Premature birth
Premature infants
Prospective Studies
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Beschreibung
Zusammenfassung:Management of pain in very low birth weight infants is limited by a lack of empiric knowledge about the multiple determinants of biobehavioral reactivity in infants receiving neonatal intensive care. To examine relationship of early neonatal factors and previous medication exposure to subsequent biobehavioral reactivity to acute pain of blood collection. Prospective cohort study. Methods. One hundred thirty-six very low birth weight (
ISSN:0031-4005
1098-4275
DOI:10.1542/peds.107.1.105