HPV AND BUSCHKE-LOWENSTEIN DISEASE
Human Papilloma Virus finalize its cycle outside the genital epithelial basement membrane, and the E7 gene of HPV decrease the capacity of the antigen presenting cells in the skin, facilitating the virus to stay hidden for extended periods of time sothe virusavoid the host immune response.In conclus...
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| creator | Spinu, Dan Arsenie Mischianu, Dan Marcu, Dragos Radu Diaconu, Camelia C Stanescu, Ana Maria Alexandra Mehedinţu, Claudia Socea, Bogdan Bratu, Ovidiu Gabriel Criveanu, Madalina |
| description | Human Papilloma Virus finalize its cycle outside the genital epithelial basement membrane, and the E7 gene of HPV decrease the capacity of the antigen presenting cells in the skin, facilitating the virus to stay hidden for extended periods of time sothe virusavoid the host immune response.In conclusion, E6 and E7 oncogenes damage the host cells to induce telomerase resulting in cellular immortalization of the infected cellsandcause chronic oxidative stress increasing the susceptibility of damaging the DNA and starting the way for carcinogenesis23. Imiquimod, a topically-applied aminoquinoline that is an immune modulator that induces interferon production,was considerdeffective in combination with carbon dioxide laser ablation in unstable patients, who were unable to tolerate surgery, whose tumor was positive for HPV-630. Rev Chim (Bucharest), 2018; 69(8): 2245-50 11 Stanculescu, R; Bratila, E; Bausic, V; Vladescu, T. The triage of low-grade cytological abnormalities by the immunocytological expression of cyclin-dependent kinase inhibitor p16INK4a versus human papillomavirus test: a real possibility to predict cervical intraepithelial neoplasia CIN2 or CIN2+. Stanculescu, R; Bratila, E; Bausic, V; Vladescu, T. The triage of low-grade cytological abnormalities by the immunocytological expression of cyclin-dependent kinase inhibitor p16INK4a versus human papillomavirus test: a real possibility to predict cervical intraepithelial neoplasia CIN2 or CIN2+. |
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Imiquimod, a topically-applied aminoquinoline that is an immune modulator that induces interferon production,was considerdeffective in combination with carbon dioxide laser ablation in unstable patients, who were unable to tolerate surgery, whose tumor was positive for HPV-630. Rev Chim (Bucharest), 2018; 69(8): 2245-50 11 Stanculescu, R; Bratila, E; Bausic, V; Vladescu, T. The triage of low-grade cytological abnormalities by the immunocytological expression of cyclin-dependent kinase inhibitor p16INK4a versus human papillomavirus test: a real possibility to predict cervical intraepithelial neoplasia CIN2 or CIN2+. Stanculescu, R; Bratila, E; Bausic, V; Vladescu, T. The triage of low-grade cytological abnormalities by the immunocytological expression of cyclin-dependent kinase inhibitor p16INK4a versus human papillomavirus test: a real possibility to predict cervical intraepithelial neoplasia CIN2 or CIN2+.</description><identifier>ISSN: 2247-4455</identifier><identifier>EISSN: 2285-9632</identifier><language>eng</language><publisher>Targu-Jiu: University Constantin Brancusi of Târgu-Jiu</publisher><subject>Abnormalities ; Antigen-presenting cells ; Antigens ; Carbon dioxide ; Carbon dioxide lasers ; Carcinogens ; Cyclin-dependent kinase ; Damage ; Deoxyribonucleic acid ; DNA ; DNA damage ; E7 gene ; Enzyme inhibitors ; Herpes viruses ; Human papillomavirus ; Imiquimod ; Immortalization ; Immune response ; Immune system ; Infections ; Inhibitors ; INK4a protein ; Interferon ; Kinases ; Laser ablation ; Literature reviews ; Medical practices ; Medical screening ; Medicine ; Metastasis ; Military medicine ; Oxidative stress ; p16 Protein ; Patients ; Skin ; Stress ; Surgery ; Telomerase ; Tumors ; Viral infections ; Viruses ; Warts</subject><ispartof>Research and science today, 2019-01, p.172-181</ispartof><rights>2019. 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Imiquimod, a topically-applied aminoquinoline that is an immune modulator that induces interferon production,was considerdeffective in combination with carbon dioxide laser ablation in unstable patients, who were unable to tolerate surgery, whose tumor was positive for HPV-630. Rev Chim (Bucharest), 2018; 69(8): 2245-50 11 Stanculescu, R; Bratila, E; Bausic, V; Vladescu, T. The triage of low-grade cytological abnormalities by the immunocytological expression of cyclin-dependent kinase inhibitor p16INK4a versus human papillomavirus test: a real possibility to predict cervical intraepithelial neoplasia CIN2 or CIN2+. Stanculescu, R; Bratila, E; Bausic, V; Vladescu, T. The triage of low-grade cytological abnormalities by the immunocytological expression of cyclin-dependent kinase inhibitor p16INK4a versus human papillomavirus test: a real possibility to predict cervical intraepithelial neoplasia CIN2 or CIN2+.</description><subject>Abnormalities</subject><subject>Antigen-presenting cells</subject><subject>Antigens</subject><subject>Carbon dioxide</subject><subject>Carbon dioxide lasers</subject><subject>Carcinogens</subject><subject>Cyclin-dependent kinase</subject><subject>Damage</subject><subject>Deoxyribonucleic acid</subject><subject>DNA</subject><subject>DNA damage</subject><subject>E7 gene</subject><subject>Enzyme inhibitors</subject><subject>Herpes viruses</subject><subject>Human papillomavirus</subject><subject>Imiquimod</subject><subject>Immortalization</subject><subject>Immune response</subject><subject>Immune system</subject><subject>Infections</subject><subject>Inhibitors</subject><subject>INK4a 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of damaging the DNA and starting the way for carcinogenesis23. Imiquimod, a topically-applied aminoquinoline that is an immune modulator that induces interferon production,was considerdeffective in combination with carbon dioxide laser ablation in unstable patients, who were unable to tolerate surgery, whose tumor was positive for HPV-630. Rev Chim (Bucharest), 2018; 69(8): 2245-50 11 Stanculescu, R; Bratila, E; Bausic, V; Vladescu, T. The triage of low-grade cytological abnormalities by the immunocytological expression of cyclin-dependent kinase inhibitor p16INK4a versus human papillomavirus test: a real possibility to predict cervical intraepithelial neoplasia CIN2 or CIN2+. Stanculescu, R; Bratila, E; Bausic, V; Vladescu, T. The triage of low-grade cytological abnormalities by the immunocytological expression of cyclin-dependent kinase inhibitor p16INK4a versus human papillomavirus test: a real possibility to predict cervical intraepithelial neoplasia CIN2 or CIN2+.</abstract><cop>Targu-Jiu</cop><pub>University Constantin Brancusi of Târgu-Jiu</pub><oa>free_for_read</oa></addata></record> |
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| source | DOAJ Directory of Open Access Journals; HeinOnline Law Journal Library; EZB-FREE-00999 freely available EZB journals |
| subjects | Abnormalities Antigen-presenting cells Antigens Carbon dioxide Carbon dioxide lasers Carcinogens Cyclin-dependent kinase Damage Deoxyribonucleic acid DNA DNA damage E7 gene Enzyme inhibitors Herpes viruses Human papillomavirus Imiquimod Immortalization Immune response Immune system Infections Inhibitors INK4a protein Interferon Kinases Laser ablation Literature reviews Medical practices Medical screening Medicine Metastasis Military medicine Oxidative stress p16 Protein Patients Skin Stress Surgery Telomerase Tumors Viral infections Viruses Warts |
| title | HPV AND BUSCHKE-LOWENSTEIN DISEASE |
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