Synthesis, Structure, and Anti-Inflammatory Activity of Functionally Substituted Chalcones and Their Derivatives

Synthesis, Structure, and Anti-Inflammatory Activity of Functionally Substituted Chalcones and Their Derivatives

Functionally substituted chalcones, pyrazolines, and flavonones have been synthesized. Their structure has been studied by means of 1 H and 13 C NMR spectroscopy, including COSY and HMQC experiments. Anti-inflammatory activity of the synthesized chalcones, pyrazolines, and flavonones has been evalua...

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Veröffentlicht in:Russian journal of general chemistry 2019-07, Vol.89 (7), p.1360-1367
Hauptverfasser: Nurkenov, O. A., Ibraev, M. K., Schepetkin, I. A., Khlebnikov, A. I., Seilkhanov, T. M., Arinova, A. E., Isabaeva, M. B.
Format: Artikel
Sprache:eng
Schlagworte:
Anti-inflammatory drugs
Antifungal agents
Bioflavonoids
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Flavones
Flavonoids
Heterocyclic compounds
NMR spectroscopy
Nuclear magnetic resonance spectroscopy
Substitutes
Synthesis
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Zusammenfassung:Functionally substituted chalcones, pyrazolines, and flavonones have been synthesized. Their structure has been studied by means of 1 H and 13 C NMR spectroscopy, including COSY and HMQC experiments. Anti-inflammatory activity of the synthesized chalcones, pyrazolines, and flavonones has been evaluated.
ISSN:1070-3632
1608-3350
DOI:10.1134/S1070363219070028