Dietary fish oil increases IL-4 secretion by murine splenocytes by an effect on accessory cells

Dietary fish oil increases IL-4 secretion by murine splenocytes by an effect on accessory cells

The results from the present study demonstrate that dietary fish oil directs the immune response of splenocytes towards a Th2 phenotype and that the effects of dietary fish oil on secretion of Th2 type cytokines are mediated by its effect on CD11b+ accessory cells.

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Veröffentlicht in:Proceedings of the Nutrition Society 2008-05, Vol.67 (OCE1), Article E62
Hauptverfasser: Petursdottir, D. H., Hardardottir, I.
Format: Artikel
Sprache:eng
Schlagworte:
Cells
Fish oils
Immune response
Nutrition
Rodents
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Beschreibung
Zusammenfassung:The results from the present study demonstrate that dietary fish oil directs the immune response of splenocytes towards a Th2 phenotype and that the effects of dietary fish oil on secretion of Th2 type cytokines are mediated by its effect on CD11b+ accessory cells.
ISSN:0029-6651
1475-2719
DOI:10.1017/S002966510800671X