Early features of systemic and adipose-tissue low-grade inflammation in a model of postprandial endothelial dysfunction

Early features of systemic and adipose-tissue low-grade inflammation in a model of postprandial endothelial dysfunction

[...] the present study has investigated whether a high-fat load can induce at a very early stage (1) the expression of endothelial adhesion markers on blood leucocytes and (2) the nuclear translocation of NF-κB, a transcription factor known to activate target genes implicated in the inflammatory c...

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Veröffentlicht in:Proceedings of the Nutrition Society 2008-05, Vol.67 (OCE5), Article E159
Hauptverfasser: Magne, J., Fischer, R., Mariotti, F., Mathe, V., Giraudet, F., Tome, D., Huneau, J. F.
Format: Artikel
Sprache:eng
Schlagworte:
Adhesion
Body fat
Rodents
Translocation
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Zusammenfassung:[...] the present study has investigated whether a high-fat load can induce at a very early stage (1) the expression of endothelial adhesion markers on blood leucocytes and (2) the nuclear translocation of NF-κB, a transcription factor known to activate target genes implicated in the inflammatory cascade including cytokine production and the expression of leucocyte-adhesion molecules.
ISSN:0029-6651
1475-2719
DOI:10.1017/S002966510800791X