Antagonistic proliferative activities of adiponectin and leptin in breast cancer: study on MCF7 cells

Antagonistic proliferative activities of adiponectin and leptin in breast cancer: study on MCF7 cells

Adiponectin mediates an antiproliferative response in breast cancer cells whereas leptin stimulates the growth of MCF7 cells, indicating that these adipokines exert antagonistic activities on breast cancer cell proliferation.

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Veröffentlicht in:Proceedings of the Nutrition Society 2008-05, Vol.67 (OCE5), Article E184
Hauptverfasser: Jardé, T., Caldefie-Chézet, F., Damez, M., Mishellany, F., Buechler, C., Bernard-Gallon, D., Penault-Llorca, F., Guillot, J., Vasson, M. P.
Format: Artikel
Sprache:eng
Schlagworte:
Breast cancer
Cells
Medical research
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Zusammenfassung:Adiponectin mediates an antiproliferative response in breast cancer cells whereas leptin stimulates the growth of MCF7 cells, indicating that these adipokines exert antagonistic activities on breast cancer cell proliferation.
ISSN:0029-6651
1475-2719
DOI:10.1017/S0029665108008161