PUFA in the pathogenesis and treatment of patients with multiple sclerosis
Cytokine dysregulation has been found in peripheral blood mononuclear cells (PBMC) during the relapse-remitting phases of MS, i.e. raised TNFα and IL-1β and lack of regulatory transforming growth factor β (TGFβ) production(1), and in an animal model of MS a protective effect of γ-linolenic acid...
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Veröffentlicht in: | Proceedings of the Nutrition Society 2008-05, Vol.67 (OCE1), Article E21 |
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Hauptverfasser: | , , , , |
Format: | Artikel |
Sprache: | eng |
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Online-Zugang: | Volltext |
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Zusammenfassung: | Cytokine dysregulation has been found in peripheral blood mononuclear cells (PBMC) during the relapse-remitting phases of MS, i.e. raised TNFα and IL-1β and lack of regulatory transforming growth factor β (TGFβ) production(1), and in an animal model of MS a protective effect of γ-linolenic acid (GLA; 18: 3n-6)-rich borage oil associated with raised TGFβ(2). |
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ISSN: | 0029-6651 1475-2719 |
DOI: | 10.1017/S0029665108006307 |