New Benzylated Alkamide from the Roots of Lepidium meyenii

New Benzylated Alkamide from the Roots of Lepidium meyenii

A new benzylated alkamide, N-(3-methoxybenzyl)hexadec-9Z-enamide ( 1 ), and a known analogue ( 2 ) were isolated from the roots of Lepidium meyenii. Their structures were elucidated by extensive NMR and MS spectroscopic analyses. All the isolated alkamides were evaluated for their cytotoxicity again...

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Veröffentlicht in:Chemistry of natural compounds 2019-07, Vol.55 (4), p.696-699
Hauptverfasser: Liu, W. X., Dong, M., Zhang, R. Q., Ma, Z. H., Yang, Q. F., Chen, Y. J., Ye, Y. Q., Liao, L. M., Cheng, P., Jiang, Z. Y., Zhou, M.
Format: Artikel
Sprache:eng
Schlagworte:
Functional foods
Medicine
NMR
Nuclear magnetic resonance
Organic Chemistry
Pharmacy
Plant Sciences
Roots
Toxicity
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Zusammenfassung:A new benzylated alkamide, N-(3-methoxybenzyl)hexadec-9Z-enamide ( 1 ), and a known analogue ( 2 ) were isolated from the roots of Lepidium meyenii. Their structures were elucidated by extensive NMR and MS spectroscopic analyses. All the isolated alkamides were evaluated for their cytotoxicity against five human cancer cell lines but found to be insignificant at concentrations up to 40 μM.
ISSN:0009-3130
1573-8388
DOI:10.1007/s10600-019-02781-w