The phosphotransferase system of Streptomyces coelicolor is biased for N-aceteylglucosamine metabolism

The phosphotransferase system of Streptomyces coelicolor is biased for N-aceteylglucosamine metabolism

Mutation of the crr-ptsI gene locus revealed that Streptomyces coelicolor uses the phosphotransferase system (PTS) for N-acetylglucosamine uptake. crr, ptsI, and ptsH, which encode the three general PTS phosphotransferases, are induced by N-acetylglucosamine but not by other PTS substrates. Thus, th...

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Veröffentlicht in:Journal of bacteriology 2003-12, Vol.185 (23), p.7019
Hauptverfasser: Nothaft, Harald, Dresel, Dagmar, Willimek, Andreas, Mahr, Kerstin
Format: Artikel
Sprache:eng
Schlagworte:
Bacteriology
Metabolism
Mutation
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Zusammenfassung:Mutation of the crr-ptsI gene locus revealed that Streptomyces coelicolor uses the phosphotransferase system (PTS) for N-acetylglucosamine uptake. crr, ptsI, and ptsH, which encode the three general PTS phosphotransferases, are induced by N-acetylglucosamine but not by other PTS substrates. Thus, the S. coelicolor PTS is biased for N-acetylglucosamine utilization, a novel feature that distinguishes this PTS from others. [PUBLICATION ABSTRACT]
ISSN:0021-9193
1098-5530