Three modifications in the D and T arms of tRNA influence translation in Escherichia coli and expression of virulene genes in Shigella flexneri
The modified nucleosides 2'-O-methylguanosine, present at position 18, 5-methyluridine, present at position 54, and pseudouridine, present at position 55, are located in the D and T arms of tRNAs and are close in space in the three-dimensional structure of this molecule in the bacterium Escheri...
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| Veröffentlicht in: | Journal of bacteriology 2002-10, Vol.184 (19), p.5348 |
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| creator | Urbonavicius, Jaunius Durand, Jerome M B Bjork, Glenn R |
| description | The modified nucleosides 2'-O-methylguanosine, present at position 18, 5-methyluridine, present at position 54, and pseudouridine, present at position 55, are located in the D and T arms of tRNAs and are close in space in the three-dimensional structure of this molecule in the bacterium Escherichia coli. The formation of these modified nucleosides is catalyzed by the product of genes trmH, trmA, and truB. |
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| ispartof | Journal of bacteriology, 2002-10, Vol.184 (19), p.5348 |
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| language | eng |
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| source | Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
| subjects | Bacteria Bacteriology Genes Mutation Ribonucleic acid RNA |
| title | Three modifications in the D and T arms of tRNA influence translation in Escherichia coli and expression of virulene genes in Shigella flexneri |
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