Cloning and characterization of the Streptomyces peucetis dnmZUV genes encoding three enzumes required for biosynthesis of the daunorubicin precursor thymidine diphospho-L-daunosamine

Characterization of the dnmZ, dnmU, and dnmV genes from the daunorubicin-producer Streptomyces peucetius by DNA sequence analysis indicated that these genes encode a protein of unknown function plus a putative thymidine diphospho-4-ket-6-deoxyglucose-3(5)-epimerase and thymidine diphospho-4-ketodeox...

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Veröffentlicht in:Journal of bacteriology 1997-07, Vol.179 (13), p.4446
Hauptverfasser: Otten, Sharee I, Gallo, Mark A, Madduri, Krishnamurthy, Liu, Xiaochun, Hutchinson, C Richard
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Sprache:eng
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Zusammenfassung:Characterization of the dnmZ, dnmU, and dnmV genes from the daunorubicin-producer Streptomyces peucetius by DNA sequence analysis indicated that these genes encode a protein of unknown function plus a putative thymidine diphospho-4-ket-6-deoxyglucose-3(5)-epimerase and thymidine diphospho-4-ketodeoxyhexulose reductase, respectively.
ISSN:0021-9193
1098-5530