Trypsin mediates growth phase-dependent transcriptional regulation of genes involved in biosynthesis of Ruminococcin A, a lantibiotic produced by a Ruminococcus gnavus strain from a

Trypsin mediates growth phase-dependent transcriptional regulation of genes involved in biosynthesis of Ruminococcin A, a lantibiotic produced by a Ruminococcus gnavus strain from a

Ruminococcin A (RumA) is a trypsin-dependent lantibiotic produced by Ruminococcus gnavus E1, a gram-positive strict anaerobic strain isolated from a human intestinal microbiota. A 12.8-kb region from R. gnavus E1 chromosome, containing the biosynthetic gene cluster of RumA, has been cloned and seque...

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Veröffentlicht in:Journal of bacteriology 2002-01, Vol.184 (1), p.18
Hauptverfasser: Gomez, Ana, Ladire, Monique, Marcille, Francoise, Fons, Michel
Format: Artikel
Sprache:eng
Schlagworte:
Bacteria
Bacteriology
Genes
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Zusammenfassung:Ruminococcin A (RumA) is a trypsin-dependent lantibiotic produced by Ruminococcus gnavus E1, a gram-positive strict anaerobic strain isolated from a human intestinal microbiota. A 12.8-kb region from R. gnavus E1 chromosome, containing the biosynthetic gene cluster of RumA, has been cloned and sequenced.
ISSN:0021-9193
1098-5530