Only the N-terminal domain of FtsK functions in cell division

Only the N-terminal domain of FtsK functions in cell division

Deletion of ftsK results in the inhibition of cell division, but this inhibition can be reversed by a plasmid carrying only the first -17% of ftsK. The division block can be suppressed in most mutants by deletion of dacA, which codes for the D-alanine:D-alanine carboxypeptidase PBP5, or in all mutan...

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Veröffentlicht in:Journal of bacteriology 1998-09, Vol.180 (17), p.4620
Hauptverfasser: Draper, G Craig, McLennan, Neil, Begg, Ken, Masters, Millicent, Donachie, William D
Format: Artikel
Sprache:eng
Schlagworte:
Bacteria
Bacteriology
Cellular biology
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Zusammenfassung:Deletion of ftsK results in the inhibition of cell division, but this inhibition can be reversed by a plasmid carrying only the first -17% of ftsK. The division block can be suppressed in most mutants by deletion of dacA, which codes for the D-alanine:D-alanine carboxypeptidase PBP5, or in all mutants by overexpression of ftsN.
ISSN:0021-9193
1098-5530