Nano Structure of Hydroxyapatite and its modern approach in Pharmaceutical Science

Hydroxyapatite being bioactive in nature is highly compatible with the tissues and bones and has a very wide spectrum of activity to treat highly infectious disease such as cancer. [...]the study is focused on its applicability to treat diseases such as bone cancer, bone diseases, microbial infectio...

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Veröffentlicht in:Research journal of pharmacy and technology 2019-03, Vol.12 (3), p.1463-1472
Hauptverfasser: Singh, Sushma, Pal, Abhisek, Mohanty, Sangeeta
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Sprache:eng
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Zusammenfassung:Hydroxyapatite being bioactive in nature is highly compatible with the tissues and bones and has a very wide spectrum of activity to treat highly infectious disease such as cancer. [...]the study is focused on its applicability to treat diseases such as bone cancer, bone diseases, microbial infection etc, also involving discussion on nanohydroxyapatite synthesis and its various applications. Henceforth, the build out of synthesis procedures for nanoparticles is a steadily evolving branch of nanotechnology. [...]the very first attempt of every researcher is the modification of various properties of nanoparticles such as- bioactivity, morphology and particle size, as a result of which large number of techniques to synthesize nanohydroxyapatite has been developed. Usually, it involves dispersing of H2O with high dielectric constant in oil with low dielectric constant. [...]to control interfacial tension between two unmixable phases, inclusion of surface active agents is mandatory. [...]green synthesis can be an effective method of developing nHA with antibacterial properties [103].
ISSN:0974-3618
0974-360X
0974-306X
DOI:10.5958/0974-360X.2019.00243.9