Assessment of Antioxidant and Antiangiogenic Activities of Ethanolic Root extract of Cassia   occidentalis

In the adult, except for a few physiological processes such as menses, wound healing, and placental formation, all angiogenic processes are pathologic.3-5 By blocking the development of new blood vessels, one hopes to cut off the tumor's supply of oxygen and nutrients and, therefore, its growth and spread to other parts of the body.6-8 The current ongoing researches are approving the plant can be useful in malignancies and at various levels and with different mechanisms.9 C. occidentalis is a small herb that grows all over India. Cassia species includes Cassia javanica, Cassia grandis, Cassia roxburghii, Cassia abbreviata, and Cassia notabilis respectively. [...]the present investigation carried out an indepth study regard the C. occidentalis ethanolic root for its antioxidant and antiangiogenic activities. Angiogenesis is defined as new blood vessels Formation from the existing vascular bed, which plays an hallmarks of cancer. Because of various factors like genetically instability and tumor blood vessels to normal vessels difference, in all types of cancer they are potential targets in therapy. [...]Cassia occidentalis can be used as a potent antiangiogenic agent.