The Myth and The fact on Naringin-A Review

[...]all the doctors counsel the patients not to have grape fruit with many of the drugs. Disruption of lipid and carbohydrate homoeostasis helps in the development of prevalent metabolic diseases such as obesity, diabetes, and atherosclerosis. [...]molecules that can reduce insulin dependence and regulate dyslipidemia will have a dramatic effect on public health. During inflammation, the inflammatory cytokines and bacterial products induces the formation of large amounts of nitric oxide by inducible nitric oxide synthase (iNOS). [...]the compounds that inhibit nitric oxide production have anti-inflammatory effects. The ED 50 value against pylorus - ligated rats was significantly greater than that against restraint rats. [...]the study confirms the naringenin and naringin possess a strong anti-ulcer protective property on rats by the mechanism of inhibiting the formation and release of endogenous histamine in the gastric mucosa66.