Oral Dispersible Films, Novel Technology for the Delivery of Drugs

Disadvantages: * It is difficult to incorporate high dose. * Only limited amount of drug can be incorporated. * Drug penetration enhancement is more. * Uniformity of dose is a challenge. * The techniques like iontophoresis can't be applied in order to improve the bioavailability, as well as pen...

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Veröffentlicht in:Research journal of pharmacy and technology 2019, Vol.12 (1), p.425-428
Hauptverfasser: Jose, Jobin, Ashwini, P B, Nayak, Prashant, Charyulu, R Narayana
Format: Artikel
Sprache:eng
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Zusammenfassung:Disadvantages: * It is difficult to incorporate high dose. * Only limited amount of drug can be incorporated. * Drug penetration enhancement is more. * Uniformity of dose is a challenge. * The techniques like iontophoresis can't be applied in order to improve the bioavailability, as well as penetration for poorly absorbed drugs. Because they may cause damage to oral mucosa9. [...]the solution is casted on the Petri plate and dried in air oven at 40-50°C. Then film is peeled and cut. [...]the solid dispersions are shaped in to films by means of dyes. Since it has fast disintegration and fast dissolution properties associated with better safety and efficacy.
ISSN:0974-3618
0974-360X
0974-306X
DOI:10.5958/0974-360X.2019.00077.5