Genetic aspects of premature ovarian failure: a literature review

Background The diagnosis of premature ovarian failure (POF) is based on the finding of amenorrhea before the age of 40 years associated with follicle-stimulating hormone levels in the menopausal range. It is a heterogeneous disorder affecting approximately 1% of women

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Bibliographische Detailangaben
Veröffentlicht in:	Archives of gynecology and obstetrics 2011-03, Vol.283 (3), p.635-643
Hauptverfasser:	Cordts, Emerson Barchi, Christofolini, Denise Maria, dos Santos, Aline Amaro, Bianco, Bianca, Barbosa, Caio Parente
Format:	Artikel
Sprache:	eng
Schlagworte:	Amenorrhea Chromosomes, Human, X - genetics Endocrinology Estrogens - blood Female Follicle Stimulating Hormone - blood Gene Rearrangement - genetics Gonadal Dysgenesis - genetics Gynecology Human Genetics Humans Inhibins - blood Luteinizing Hormone - blood Medicine Medicine & Public Health Obstetrics/Perinatology/Midwifery Primary Ovarian Insufficiency - genetics Reproductive Medicine Sex Chromosome Aberrations Sex Chromosome Disorders of Sex Development - genetics Trisomy - genetics Turner Syndrome - genetics
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Beschreibung
Zusammenfassung:	Background The diagnosis of premature ovarian failure (POF) is based on the finding of amenorrhea before the age of 40 years associated with follicle-stimulating hormone levels in the menopausal range. It is a heterogeneous disorder affecting approximately 1% of women
ISSN:	0932-0067 1432-0711
DOI:	10.1007/s00404-010-1815-4