Alzheimer′s disease prevention & acetyl salicylic acid: a believable story

According to this study, aspirin (acetyl salicylic acid, ASA), steroid and NSAIDs [traditional and the selective cyclooxygenase-2 (COX-2) inhibitors] showed no significant benefit in the treatment of AD. [...]these new pathways - especially in presence of acetylated COX-2 - might provide new means t...

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Veröffentlicht in:	Indian journal of medical research (New Delhi, India : 1994) India : 1994), 2014-01, Vol.140 (1), p.1-3
Hauptverfasser:	Pomponi, Massimiliano, Pomponi, Massimo
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Brain Dementia Disease prevention Drug dosages Metabolism Metabolites Signal transduction Vegetarianism Women
Online-Zugang:	Volltext
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Zusammenfassung:	According to this study, aspirin (acetyl salicylic acid, ASA), steroid and NSAIDs [traditional and the selective cyclooxygenase-2 (COX-2) inhibitors] showed no significant benefit in the treatment of AD. [...]these new pathways - especially in presence of acetylated COX-2 - might provide new means to mark the impact of essential n-3 FAs in ageing, as well as supply new preventive dietary interventions for dementia (and for the protection of synaptic loss?). [...]high fish intake - or dietary supplementation with n-3 FAs was linked to reductions in the risk of developing AD and in delaying cognitive decline in patients with very mild AD [13] .
ISSN:	0971-5916