Theoretical investigation of thermal wave model of microwave ablation applied in prostate Cancer therapy

This paper presents an hyperbolic Pennes bioheat equation in cylindrical coordinate for modeling the Microwave Ablation (MWA) applied in prostate cancer. Due to recent reports, the number of patients of prostate cancer is growing by 15 million in the world each year. Since, it is shown that application of uniform microwave in prostate area of different patients may produce different temperature, the Pennes bioheat equation is considered to study the effect of perfusion term on produced temperature profiles. The solution method is Eigen value method which results in a closed form solution. The hyperbolic behavior of temperature profiles under high heat release against Fourier model is shown. Results show the importance of tissue perfusion term in estimation of temperature profiles and establish that the thermal tissue damage is expected to initiate from 1 to 3 mm above the catheter surface and to promote up to 7 mm. The solutions can be applied as a verification branch for other numerical works and can be very useful to reduce uncertainty about MWA treatments and improve the reliability of clinical protocols giving insight to the Surgeons.