Combined orthodontic and surgical treatment in PTH1R‐negative ‘primary failure of eruption’‐like anomalies: report of two cases with satisfactory long‐term response to traction

Introduction Primary failure of eruption (PFE) is a sporadic or inherited disorder of dental eruption that can be caused by mutations in the PTH1R gene. PFE typically manifests as a severe posterior open bite. Orthodontic treatment is considered ineffective in PFE. Case presentation Here, we report two unrelated PTH1R‐negative cases of severe eruption disorders presenting several of the typical clinical features of PFE, and where we tracted the impacted teeth using Bollard bone anchors. Management We managed to obtain a satisfactory occlusion in both cases without extended ankylosis induced by the orthodontic movements based on bone anchors. Outcome These cases underline the need for a better understanding of the genetics of dental eruption disorders related to PFE before establishing strict clinical guidelines ruling out potentially efficient orthodontic management protocols within the PFE spectrum.