APPLICABILITY OF DENTAL PANORAMIC RADIOMORPHOMETRIC AND FRACTAL DIMENSION ANALYSIS IN THE EVALUATION OF ANTIEPILEPTIC DRUG-INDUCED OSTEOPOROSIS
The use of AED leads to altered bone metabolism, such as reduction in bone mineral density (BMD) and inferior levels of 25-hydroxyvitamin D (25OHD), and induced bone loss, causing: increased catabolism of active vitamin D metabolites due to hepatic enzyme induction, direct effects on bone cells, hyp...
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description | The use of AED leads to altered bone metabolism, such as reduction in bone mineral density (BMD) and inferior levels of 25-hydroxyvitamin D (25OHD), and induced bone loss, causing: increased catabolism of active vitamin D metabolites due to hepatic enzyme induction, direct effects on bone cells, hyperparathyroidism and calcitonin deficiency [2]. According to these results, the mean of FD1, FD2, FD3 and mean-FD value obtained by averaging the FD values of 4 different regions were significantly higher in controls (p=0.027, p=0.001, p=0.032, and p=0.006 respectively) than in patients. [14] In another study conducted in Thailand, the authors revealed that 36% of 123 adult epileptic patients had osteopenia, whereas 4.1% had osteoporosis. 25 (20%) epilepsy patients had vitamin D deficiency, no correlation being found between BMD values and vitamin D status. Phabphal K, Geater A, Leelawattana R, Sathirapunya P, Sattawatcharawanich S, Limapichat K. Prevalence and risk factors of low bone mineral density and 25-hydroxyvitamin D status in young healthy epileptic adult patients in a tropical Asian country taking antiepileptic drug. |
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According to these results, the mean of FD1, FD2, FD3 and mean-FD value obtained by averaging the FD values of 4 different regions were significantly higher in controls (p=0.027, p=0.001, p=0.032, and p=0.006 respectively) than in patients. [14] In another study conducted in Thailand, the authors revealed that 36% of 123 adult epileptic patients had osteopenia, whereas 4.1% had osteoporosis. 25 (20%) epilepsy patients had vitamin D deficiency, no correlation being found between BMD values and vitamin D status. Phabphal K, Geater A, Leelawattana R, Sathirapunya P, Sattawatcharawanich S, Limapichat K. Prevalence and risk factors of low bone mineral density and 25-hydroxyvitamin D status in young healthy epileptic adult patients in a tropical Asian country taking antiepileptic drug.</description><identifier>ISSN: 2066-6063</identifier><identifier>EISSN: 2392-8018</identifier><language>eng</language><publisher>Iasi: Apollonia University of Iasi, Medical Dentistry Faculty</publisher><subject>25-Hydroxyvitamin D ; Age ; Antiepileptic agents ; Bone density ; Bone loss ; Bone mineral density ; Bone turnover ; Calcitonin ; Chronic illnesses ; Dental implants ; Drugs ; Epilepsy ; Fractals ; Hyperparathyroidism ; Metabolism ; Metabolites ; Morphology ; Osteopenia ; Osteoporosis ; Quality ; Risk factors ; Transplants & implants ; Vitamin D ; Vitamin deficiency ; Womens health</subject><ispartof>International journal of medical dentistry, 2019-04, Vol.9 (2), p.201-207</ispartof><rights>2019. 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According to these results, the mean of FD1, FD2, FD3 and mean-FD value obtained by averaging the FD values of 4 different regions were significantly higher in controls (p=0.027, p=0.001, p=0.032, and p=0.006 respectively) than in patients. [14] In another study conducted in Thailand, the authors revealed that 36% of 123 adult epileptic patients had osteopenia, whereas 4.1% had osteoporosis. 25 (20%) epilepsy patients had vitamin D deficiency, no correlation being found between BMD values and vitamin D status. Phabphal K, Geater A, Leelawattana R, Sathirapunya P, Sattawatcharawanich S, Limapichat K. Prevalence and risk factors of low bone mineral density and 25-hydroxyvitamin D status in young healthy epileptic adult patients in a tropical Asian country taking antiepileptic drug.</description><subject>25-Hydroxyvitamin D</subject><subject>Age</subject><subject>Antiepileptic agents</subject><subject>Bone density</subject><subject>Bone loss</subject><subject>Bone mineral density</subject><subject>Bone turnover</subject><subject>Calcitonin</subject><subject>Chronic illnesses</subject><subject>Dental implants</subject><subject>Drugs</subject><subject>Epilepsy</subject><subject>Fractals</subject><subject>Hyperparathyroidism</subject><subject>Metabolism</subject><subject>Metabolites</subject><subject>Morphology</subject><subject>Osteopenia</subject><subject>Osteoporosis</subject><subject>Quality</subject><subject>Risk factors</subject><subject>Transplants & implants</subject><subject>Vitamin D</subject><subject>Vitamin deficiency</subject><subject>Womens health</subject><issn>2066-6063</issn><issn>2392-8018</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqNTMtKxDAULaLgoPMPAdeFJhlDu7wmt_ZCmhvSVJjV4GJcDOLo1PkOf9kM-AGezTmc11W1UrpTddvI9rroxpjaNEbfVutlOTQF3UZqKVfVD8ToycITecpbwb1wGDJ4ESFwgpGsSOCIR05x4BFzKg4EJ_oE9tJzNGKYiENxwW8nmgQFkQcU-AJ-hnyJyi2ETBjJY8zlwaX5uabgZotO8JSRIycu4_vq5u31fdmv__iueugx26H-PB2_zvvle3c4nk8fJdop9ailaTvV6v-1fgGgqUqY</recordid><startdate>20190401</startdate><enddate>20190401</enddate><creator>Ustaoğlu, Gülbahar</creator><creator>Bulut, Duygu Göller</creator><creator>Bayrak, Seval</creator><general>Apollonia University of Iasi, Medical Dentistry Faculty</general><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>BYOGL</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M7P</scope><scope>NAPCQ</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope></search><sort><creationdate>20190401</creationdate><title>APPLICABILITY OF DENTAL PANORAMIC RADIOMORPHOMETRIC AND FRACTAL DIMENSION ANALYSIS IN THE EVALUATION OF ANTIEPILEPTIC DRUG-INDUCED OSTEOPOROSIS</title><author>Ustaoğlu, Gülbahar ; Bulut, Duygu Göller ; Bayrak, Seval</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-proquest_journals_22531689283</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>25-Hydroxyvitamin D</topic><topic>Age</topic><topic>Antiepileptic agents</topic><topic>Bone density</topic><topic>Bone loss</topic><topic>Bone mineral density</topic><topic>Bone turnover</topic><topic>Calcitonin</topic><topic>Chronic illnesses</topic><topic>Dental implants</topic><topic>Drugs</topic><topic>Epilepsy</topic><topic>Fractals</topic><topic>Hyperparathyroidism</topic><topic>Metabolism</topic><topic>Metabolites</topic><topic>Morphology</topic><topic>Osteopenia</topic><topic>Osteoporosis</topic><topic>Quality</topic><topic>Risk factors</topic><topic>Transplants & implants</topic><topic>Vitamin D</topic><topic>Vitamin deficiency</topic><topic>Womens health</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ustaoğlu, Gülbahar</creatorcontrib><creatorcontrib>Bulut, Duygu Göller</creatorcontrib><creatorcontrib>Bayrak, Seval</creatorcontrib><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>East Europe, Central Europe Database</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Biological Science Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Access via ProQuest (Open Access)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><jtitle>International journal of medical dentistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ustaoğlu, Gülbahar</au><au>Bulut, Duygu Göller</au><au>Bayrak, Seval</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>APPLICABILITY OF DENTAL PANORAMIC RADIOMORPHOMETRIC AND FRACTAL DIMENSION ANALYSIS IN THE EVALUATION OF ANTIEPILEPTIC DRUG-INDUCED OSTEOPOROSIS</atitle><jtitle>International journal of medical dentistry</jtitle><date>2019-04-01</date><risdate>2019</risdate><volume>9</volume><issue>2</issue><spage>201</spage><epage>207</epage><pages>201-207</pages><issn>2066-6063</issn><eissn>2392-8018</eissn><abstract>The use of AED leads to altered bone metabolism, such as reduction in bone mineral density (BMD) and inferior levels of 25-hydroxyvitamin D (25OHD), and induced bone loss, causing: increased catabolism of active vitamin D metabolites due to hepatic enzyme induction, direct effects on bone cells, hyperparathyroidism and calcitonin deficiency [2]. According to these results, the mean of FD1, FD2, FD3 and mean-FD value obtained by averaging the FD values of 4 different regions were significantly higher in controls (p=0.027, p=0.001, p=0.032, and p=0.006 respectively) than in patients. [14] In another study conducted in Thailand, the authors revealed that 36% of 123 adult epileptic patients had osteopenia, whereas 4.1% had osteoporosis. 25 (20%) epilepsy patients had vitamin D deficiency, no correlation being found between BMD values and vitamin D status. Phabphal K, Geater A, Leelawattana R, Sathirapunya P, Sattawatcharawanich S, Limapichat K. Prevalence and risk factors of low bone mineral density and 25-hydroxyvitamin D status in young healthy epileptic adult patients in a tropical Asian country taking antiepileptic drug.</abstract><cop>Iasi</cop><pub>Apollonia University of Iasi, Medical Dentistry Faculty</pub><oa>free_for_read</oa></addata></record> |
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subjects | 25-Hydroxyvitamin D Age Antiepileptic agents Bone density Bone loss Bone mineral density Bone turnover Calcitonin Chronic illnesses Dental implants Drugs Epilepsy Fractals Hyperparathyroidism Metabolism Metabolites Morphology Osteopenia Osteoporosis Quality Risk factors Transplants & implants Vitamin D Vitamin deficiency Womens health |
title | APPLICABILITY OF DENTAL PANORAMIC RADIOMORPHOMETRIC AND FRACTAL DIMENSION ANALYSIS IN THE EVALUATION OF ANTIEPILEPTIC DRUG-INDUCED OSTEOPOROSIS |
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