Three-Component Reaction of Dimedone with Aromatic Aldehydes and 5-Aminotetrazole

Reactions of dimedone with aromatic aldehyde and 5-aminotetrazole monohydrate proceeded with the formation of 9-aryl-6,6-dimethyl-5,6,7,9-tetrahydrotetrazolo[5,1- b ]quinazoline-8(4 H )-ones or 9-aryl-3,3,6,6-tetramethyl-3,4,6,7-tetrahydro-2 H -xanthene-1,8(5 H ,9 H )-diones depending on the nature...

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Veröffentlicht in:Russian journal of general chemistry 2019-05, Vol.89 (5), p.881-885
Hauptverfasser: Gein, V. L., Prudnikova, A. N., Kurbatova, A. A., Dmitriev, M. V., Novikova, V. V., Rudakova, I. P., Starikov, A. L.
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container_end_page 885
container_issue 5
container_start_page 881
container_title Russian journal of general chemistry
container_volume 89
creator Gein, V. L.
Prudnikova, A. N.
Kurbatova, A. A.
Dmitriev, M. V.
Novikova, V. V.
Rudakova, I. P.
Starikov, A. L.
description Reactions of dimedone with aromatic aldehyde and 5-aminotetrazole monohydrate proceeded with the formation of 9-aryl-6,6-dimethyl-5,6,7,9-tetrahydrotetrazolo[5,1- b ]quinazoline-8(4 H )-ones or 9-aryl-3,3,6,6-tetramethyl-3,4,6,7-tetrahydro-2 H -xanthene-1,8(5 H ,9 H )-diones depending on the nature of substituent in aromatic aldehyde. Antimicrobial, antifungal and analgesic activities of the synthesized compounds were studied.
doi_str_mv 10.1134/S1070363219050049
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source SpringerNature Journals
subjects Aldehydes
Alfuzosin
Aromatic compounds
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Diketones
Fungicides
Heterocyclic compounds
title Three-Component Reaction of Dimedone with Aromatic Aldehydes and 5-Aminotetrazole
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