Three-Component Reaction of Dimedone with Aromatic Aldehydes and 5-Aminotetrazole

Three-Component Reaction of Dimedone with Aromatic Aldehydes and 5-Aminotetrazole

Reactions of dimedone with aromatic aldehyde and 5-aminotetrazole monohydrate proceeded with the formation of 9-aryl-6,6-dimethyl-5,6,7,9-tetrahydrotetrazolo[5,1- b ]quinazoline-8(4 H )-ones or 9-aryl-3,3,6,6-tetramethyl-3,4,6,7-tetrahydro-2 H -xanthene-1,8(5 H ,9 H )-diones depending on the nature...

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Veröffentlicht in:Russian journal of general chemistry 2019-05, Vol.89 (5), p.881-885
Hauptverfasser: Gein, V. L., Prudnikova, A. N., Kurbatova, A. A., Dmitriev, M. V., Novikova, V. V., Rudakova, I. P., Starikov, A. L.
Format: Artikel
Sprache:eng
Schlagworte:
Aldehydes
Alfuzosin
Aromatic compounds
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Diketones
Fungicides
Heterocyclic compounds
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Zusammenfassung:Reactions of dimedone with aromatic aldehyde and 5-aminotetrazole monohydrate proceeded with the formation of 9-aryl-6,6-dimethyl-5,6,7,9-tetrahydrotetrazolo[5,1- b ]quinazoline-8(4 H )-ones or 9-aryl-3,3,6,6-tetramethyl-3,4,6,7-tetrahydro-2 H -xanthene-1,8(5 H ,9 H )-diones depending on the nature of substituent in aromatic aldehyde. Antimicrobial, antifungal and analgesic activities of the synthesized compounds were studied.
ISSN:1070-3632
1608-3350
DOI:10.1134/S1070363219050049