419-P: LDL Particle Size Is a Predictor of Cardiovascular Events in Cardiovascular Disease Patients with Nonalcoholic Fatty Liver Disease as Well as in Those without Nonalcoholic Fatty Liver Disease

419-P: LDL Particle Size Is a Predictor of Cardiovascular Events in Cardiovascular Disease Patients with Nonalcoholic Fatty Liver Disease as Well as in Those without Nonalcoholic Fatty Liver Disease

Nonalcoholic fatty liver disease (NAFLD) is associated with atherogenic dyslipidemia, in particular with a small LDL particle size. However, there are no data on the association between LDL particle size and cardiovascular events in cardiovascular disease patients with NAFLD. This issue is addressed...

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Veröffentlicht in:Diabetes (New York, N.Y.) N.Y.), 2019-06, Vol.68 (Supplement_1)
Hauptverfasser: LEIHERER, ANDREAS, MUENDLEIN, AXEL, SAELY, CHRISTOPH H., VONBANK, ALEXANDER, LARCHER, BARBARA, MADER, ARTHUR, DOPHEIDE, JÖRN F., BAUMGARTNER, IRIS, FRAUNBERGER, PETER, DREXEL, HEINZ
Format: Artikel
Sprache:eng
Schlagworte:
Cardiovascular disease
Cardiovascular diseases
Dyslipidemia
Fatty liver
Health risk assessment
High density lipoprotein
Liver diseases
Low density lipoprotein
Particle size
Smoking
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Zusammenfassung:Nonalcoholic fatty liver disease (NAFLD) is associated with atherogenic dyslipidemia, in particular with a small LDL particle size. However, there are no data on the association between LDL particle size and cardiovascular events in cardiovascular disease patients with NAFLD. This issue is addressed in the present study. We measured LDL particle size and concentration in 298 statin-naïve cardiovascular disease patients, of whom 141 had NAFLD. In patients with NAFLD, LDL particle size was significantly lower (21.0 vs. 21.2 nm, p
ISSN:0012-1797
1939-327X
DOI:10.2337/db19-419-P