Recent Progress of the Synthetic Studies of Biologically Active Marine Cyclic Peptides and Depsipeptides

Complete racemization-free peptide synthesis during the fragment coupling of amino acids might be a never-ending problem as long as activation of the C-Terminal carboxyl group is necessary prior to coupling with amine components.

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Bibliographische Detailangaben
Veröffentlicht in:	Chemical reviews 2005-12, Vol.105 (12), p.4441-4482
Hauptverfasser:	Hamada, Yasumasa, Shioiri, Takayuki
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Animals Chemical synthesis Cyclization Depsipeptides - chemical synthesis Depsipeptides - chemistry Marine Toxins - chemical synthesis Marine Toxins - chemistry Molecular Structure Peptides Peptides, Cyclic - chemical synthesis Peptides, Cyclic - chemistry Stereoisomerism
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Beschreibung
Zusammenfassung:	Complete racemization-free peptide synthesis during the fragment coupling of amino acids might be a never-ending problem as long as activation of the C-Terminal carboxyl group is necessary prior to coupling with amine components.
ISSN:	0009-2665 1520-6890
DOI:	10.1021/cr0406312