The Prevention of Radiocontrast-Agent–Induced Nephropathy by Hemofiltration

Preexisting renal failure confers a risk of radiocontrast-agent–induced nephropathy after percutaneous coronary interventions. This study compared preemptive hemofiltration administered in an intensive care unit (ICU) with isotonic intravenous hydration given in a step-down unit for the prevention o...

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Veröffentlicht in:	The New England journal of medicine 2003-10, Vol.349 (14), p.1333-1340
Hauptverfasser:	Marenzi, Giancarlo, Marana, Ivana, Lauri, Gianfranco, Assanelli, Emilio, Grazi, Marco, Campodonico, Jeness, Trabattoni, Daniela, Fabbiocchi, Franco, Montorsi, Piero, Bartorelli, Antonio L
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute coronary syndromes Aged Angioplasty, Balloon, Coronary - adverse effects Biological and medical sciences Blood Urea Nitrogen Cardiology Contrast agents Contrast Media - adverse effects Coronary Angiography - adverse effects Female Hemofiltration Humans Kidney Diseases - chemically induced Kidney Diseases - prevention & control Kidney Failure, Chronic - complications Male Medical sciences Miscellaneous Mortality Peritoneal dialysis Prospective Studies Radiopharmaceuticals - adverse effects Sodium Chloride - therapeutic use Toxicology
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Zusammenfassung:	Preexisting renal failure confers a risk of radiocontrast-agent–induced nephropathy after percutaneous coronary interventions. This study compared preemptive hemofiltration administered in an intensive care unit (ICU) with isotonic intravenous hydration given in a step-down unit for the prevention of contrast-agent–induced nephropathy in high-risk patients. A decrease in renal function occurred less frequently with hemofiltration (in 5 percent vs. 50 percent of patients; P
ISSN:	0028-4793 1533-4406
DOI:	10.1056/NEJMoa023204