Synthesis of 3,4-dihydroisoquinolines using nitroalkanes in polyphosphoric acid

Synthesis of 3,4-dihydroisoquinolines using nitroalkanes in polyphosphoric acid

A new method for the synthesis of 6,7-dimethoxy-3,4-dihydroisoquinoline based on the reaction of 2-(3,4-dimethoxyphenyl)ethan-1-amine (homoveratrylamine) with aliphatic nitro compounds in polyphosphoric acid (PPA) was developed.

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Veröffentlicht in:Russian chemical bulletin 2019-05, Vol.68 (5), p.1047-1051
Hauptverfasser: Aksenov, N. A., Malyuga, V. V., Abakarov, G. M., Aksenov, D. A., Voskressensky, L. G., Aksenov, A. V.
Format: Artikel
Sprache:eng
Schlagworte:
Aliphatic compounds
Chemical industry
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Full Article
Inorganic Chemistry
Management buyouts
Nitro compounds
Organic Chemistry
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Zusammenfassung:A new method for the synthesis of 6,7-dimethoxy-3,4-dihydroisoquinoline based on the reaction of 2-(3,4-dimethoxyphenyl)ethan-1-amine (homoveratrylamine) with aliphatic nitro compounds in polyphosphoric acid (PPA) was developed.
ISSN:1066-5285
1573-9171
DOI:10.1007/s11172-019-2518-z